Figure 5
FBP1 protein levels inversely correlate with TRIM28 expression in HCC patient specimens. (a) Images of IHC analysis of FBP1 and TRIM28 protein expression and hematoxylin and eosin (H&E) staining on TMA (n=75) tissue sections. Scale bars are shown as indicated. (b) Correlation analysis of the staining index (SI) of expression levels of FBP1 and TRIM28 proteins in human HCC specimens (n=75). Pearson’s product-moment correlation co-efficiency and the P-values are also shown. (c) Box plots of TRIM28 and FBP1 protein expression based on their SI in nonmalignant adjacent tissues (NAT) and HCC specimens. The P-values are also shown. (d) Box plots of TRIM28 and FBP1 protein expression based on their SI in HCC specimens at different clinical stages. G1, G2 and G3 represent well-differentiated, moderately differentiated and poorly differentiated tumors, respectively. The P-values are also shown.
