Table 3 WHV–woodchuck genome junctions identified in liver biopsies after de novo infection

From: Initial sites of hepadnavirus integration into host genome in human hepatocytes and in the woodchuck model of hepatitis B-associated hepatocellular carcinoma

Animal/ liver biopsy number

Total of virus–host junctions detected (no)

WHV sequence (nt. position)

Host sequence (bp length)

Chromosome number a

Sequence locus a

Host sequence (nt. position)

Gene a

Total of virus–virus junctions detected (no)

Cw1/M LBx2-1 h.p.i.

3

PS3200–3256

33

11

q21

95720503–95720470

MAML2

3

  

X1853–1876

16

UI

UI

UI

UI

 
  

PS2785–2934

36

15

q25

84783482–84783518

EFTUD1P1

 

Cw2/F LBx2-1 h.p.i.

5

X1913–1853

48

2

p14

69870009–69870057

AAK1

12

  

X1913–1853

118

2

p14

69784039–69784157

AAK1

 
  

X1913–1853

19

6

q14.1

83777393–8377412

KIAA1117

 
  

X1910–1853

20

20

q12

39989149–39989169

LPIN3

 
  

PS3030–3009

17

20

q13.2

178193731–178193748

PHACTR3

 

Cw4/M LBx2–3 h.p.i.

3

PS3250–3308

75

UI

UI

UI

UI

4

  

PS3251–3308

68

UI

UI

UI

UI

 
  

PS3251–3308

70

UI

UI

UI

UI

 

Cw1/M LBx3–6 w.p.i.

2

X1855–1876

16

UI

UI

UI

UI

0

  

X1854–1877

18

16b

q13b

2650–2632

NLRC5b

0

Cw2/F LBx3–6 w.p.i.

2

X1623–1501

210

UI

UI

UI

UI

0

  

X1548–1501

137

UI

UI

UI

UI

 

Cw3/F Bx3–6 w.p.i.

1

X1772–1821

81

UI

UI

UI

UI

2

Cw4/M LBx3–6 w.p.i.

2

PS3250–3308

68

UI

UI

UI

UI

4

  

X1651–1810

26

X

p21.1

18674290–18674316

HDAC-9

 
  1. Abbreviations: AAK1, AP-1 associated kinase; EFTUD1P1, elongation factor Tu GTP binding domain containing 1 pseudogene; HDAC-9, histone deacetylase-9; Kazusa cDNA 1117; KIAA1117; LPIN3, lipin-3; MAML2, mastermind-like 2; NLRC5, NLR family CARD domain containing 5; PHACTR3, phosphatase and actin regulator 3; UI, unidentified sequence.
  2. aBased on homology with human genome.
  3. bBased on homology with mouse genome.