Table 2 Gene Ontology classifying TRPV4 target proteins into their molecular functional groups and biological processes using Metacore analysis

From: TRPV4 plays a role in breast cancer cell migration via Ca2+-dependent activation of AKT and downregulation of E-cadherin cell cortex protein

#

Networks

Genes from active data

Total

P-value

1

Cytoskeleton-regulation of cytoskeleton rearrangement

β-Tubulin, 14-3-3 epsilon, Talin, 14-3-3

183

9.62E−04

2

Proteolysis-ECM remodeling

Fibronection, Clusterin and Osteopontin

85

1.17E−03

3

Cell adhesion-integrin-mediated cell-matrix adhesion

Fironection, β-Tubulin, Talin and Osteopontin

214

1.72E−03

  1. The top 3 functional networks most significantly associated with these 27 candidates are shown.