Table 3 Extracellular proteins whose expression were significantly affected by Trpv4-gene silencing alone

From: TRPV4 plays a role in breast cancer cell migration via Ca2+-dependent activation of AKT and downregulation of E-cadherin cell cortex protein

TRPV4-specific protein expression affected by Trpv4-gene silencing

Mode of secretion

MW (kDa)

% Coverage

Fold change S1_DMSO: Luc_DMSO

P-value

Fold change S3_DMSO: Luc_DMSO

P-value

Gene_Symbol=Cdk5 Cell division protein kinase 5

Exosome

33

45.55

0.59

5.17E−16

0.72

1.09E−14

Gene_Symbol=Ube2l3 Ubiquitin-conjugating enzyme E2 L3

Exosome

17

42.86

0.71

0.01

0.64

2.56E−4.0

Gene_Symbol=Pcf11 Cleavage and polyadenylation factor subunit homolog

Exosome

173

27.88

1.67

0.01

1.40

4.28E−5.0

Gene_Symbol=Nefm Neurofilament medium polypeptide

Exosome

160

44.10

1.39

0.03

1.30

4.09E−3.0