Figure 3
Rb has significant impact on fatty acid composition. (a) Levels of the indicated fatty acids in control MEFs (solid) and Rb-depleted MEFs (blank). Data represent mean+s.d. Four batches of MEFs derived from one embryo were used per one shRNA. *P<0.05, **P<0.01 by Student’s t-test. (b) Diagram of de novo synthesis of MUFAs. (c) Levels of the indicated FA 18:1 in control MEFs (solid) and Rb-depleted MEFs (blank). Data represent mean+s.d. (n=4) *P<0.05, **P<0.01 by Student’s t-test. MUFA, mono-unsaturated fatty acid.
