Table 2 EB leukemia cells transfer disease through multiple hosts

From: Spontaneous loss of B lineage transcription factors leads to pre-B leukemia in Ebf1+/–Bcl-xLTg mice

Transfer experiments

1st

2nd

3rd

4th

5th

6th

7th

8th

9th

EB 76

8/8

6/6

4/4

4/4

4/4

3/3

3/3

3/3

 

EB 54

5/5

4/4

4/4

4/4

4/4

6/6

3/3

2/2

 

EB 39

5/5

4/4

4/4

4/4

4/4

4/4

4/4

4/4

2/2

EB 15

4/4

4/4

4/4

4/4

3/3

3/3

2/2

  

EB 19

4/4

4/4

2/2

2/2

     

EB 87

4/4

3/3

3/3

3/3

     
  1. Six different Ebf1+/–Bcl-xLTgprimary tumor cell isolates were intravenously injected into sublethally irradiated Rag1-deficient recipient mice. Tumors were serially transferred through 4–9 hosts depending on the isolate. Numbers represent animals killed due to disease development with respect to the total number of recipients in the cohort (for example, 4/4=4 mice developed clinical disease out of 4 mice injected).
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