Figure 1 | Oncogenesis

Figure 1

From: Spatial distribution of disease-associated variants in three-dimensional structures of protein complexes

Figure 1

Distance between residues corresponding to nsSNVs and the nearest interaction partner (log scale). Biological data sets are shown in a darker shade. The fraction of mapped nsSNVs, for which a template with a co-resolved corresponding interaction partner is provided below boxes representing distribution of distances to protein, ligand and DNA interaction partners for each biological data set. For randomized data sets, all 10 replicas are used to create the plots. (a) Distances to the nearest protein chain. (b) Distances to the nearest ligand. (c) Distances to the nearest DNA chain.

Back to article page