Figure 2 | Oncogenesis

Figure 2

From: Spatial distribution of disease-associated variants in three-dimensional structures of protein complexes

Figure 2

Chemical difference between wild-type and mutated residues. Gray bars indicate biological data sets, light-gray bars indicate randomized data sets. Chemical distance is calculated as Euclidean distances between the end points of the vectors representing five most important numerical descriptors of physical and chemical properties80 of the wild-type and mutant amino acids.

Back to article page