Table 2 Adjusted^a ORs (95% CIs) for factors associated with the selection of cryotherapy instead of aggressive standard therapy^b in men diagnosed with incident localized prostate cancer, SEER-Medicare

Characteristics	OR	95% CI	P-value
Age (years)
75+	1.58	(1.27, 1.95)	<0.001
66–74		Referent
Race
Black/Other	0.99	(0.75, 1.29)	0.910
White		Referent
Marital status ^c
Unmarried/Unspecified	1.66	(1.33, 2.07)	<0.001
Married		Referent
Income
Lowest tertile	1.46	(1.10, 1.93)	0.008
Middle tertile	1.35	(1.03, 1.77)	0.031
Highest tertile		Referent
Region
South	1.81	(1.42, 2.31)	<0.001
North central	0.55	(0.37, 0.81)	0.003
Northeast	0.45	(0.31, 0.64)	<0.001
West		Referent
PSA (ng ml⁻¹)
0.1–⩽10		Referent
10.1–19.9	0.92	(0.69, 1.21)	0.544
⩾20	0.95	(0.65, 1.40)	0.805
Gleason score
2–6		Referent
7	1.04	(0.84, 1.29)	0.732
8–10	0.60	(0.41, 0.86)	0.006
Clinical stage
T2	1.22	(0.99, 1.50)	0.059
T1		Referent
Charlson co-morbidity score
0		Referent
1	1.41	(1.10, 1.81)	0.008
2+	1.15	(0.77, 1.71)	0.498

Abbreviations: CI, confidence interval; OR, odds ratio; SEER, Surveillance Epidemiology End Results.
^aAdjusted for patient and tumor characteristics included in the table.
^bAggressive standard therapies include radical prostatectomy, external beam radiation therapy and brachytherapy.
^cUnmarried consists of men reported being separated, divorced or widowed.

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