Figure 1
From: Extracellular vesicles for liquid biopsy in prostate cancer: where are we and where are we headed?

The cartoon represents two canonical mechanisms of EV formation from multivesicular bodies (Exo) or direct budding from the plasma membrane, as it is the case for ectosomes (MV and LO). Notably, MV and LO can reach significantly larger dimensions than Exo. EV, extracellular vesicles; LO, large oncosomes; MV, microvesicles.