Abstract
The lactose-carrying polystyrene derivative, PVLA, is known as the material suitable for the incubation of liver cells and for drug delivery systems. PVLA was dissolved in 0.1 M urea aqueous solution, and its structure was analyzed from the results of small-angle X-ray scattering and the molecular modeling. PVLA was found to have the shape of a molecular bottlebrush in solution, composed of a large pseudo helix of polystyrene backbone. The amphiphilic nature of the backbone and side chains is thought to determine the backbone conformation.
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Wataoka, I., Urakawa, H., Kobayashi, K. et al. Molecular Specification of Homopolymer of Vinylbenzyl-Lactose-Amide in Aqueous Solution. Polym J 31, 590–594 (1999). https://doi.org/10.1295/polymj.31.590
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DOI: https://doi.org/10.1295/polymj.31.590
