Abstract
Enzymatic polymerization is a powerful tool for the synthesis of functional polymeric materials. Horseradish peroxidase (HRP)-mediated vinyl polymerization in the presence of hydrogen peroxide (H2O2) and β-diketone has been successfully applied to the synthesis of functional polymer particles as follows: (i) monodisperse polymer particles were prepared by enzymatic miniemulsion polymerization using surfmer (surfactant+monomer). (ii) Polymer particles stabilized by β-diketone moieties were prepared by enzymatic emulsifier-free emulsion polymerization. (iii) A novel method of surface-initiated enzymatic graft polymerization was used to synthesize core-shell particles. These methods could offer a practical approach for the synthesis of functional polymer particles because the polymerizations can be conducted at room temperature using a mild enzymatic process.
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Acknowledgements
I thank Professor Takayuki Nakahira, Professor Keiki Kishikawa and Professor Tatsuo Taniguchi and the students of the research group, particularly Ms Haruka Fukushima, Ms Ayaka Kobayashi, Mr Satoshi Uzawa and Ms. Yuri Nannichi. This work was partly supported by a grant from the Futaba Electronics Memorial Foundation, Oil and Fat Industry Kaikan Foundation and KAKENHI.
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Kohri, M. Development of HRP-mediated enzymatic polymerization under heterogeneous conditions for the preparation of functional particles. Polym J 46, 373–380 (2014). https://doi.org/10.1038/pj.2014.13
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DOI: https://doi.org/10.1038/pj.2014.13
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