Abstract
The conduction velocities of the ulnar and posterior tibial nerves were measured in a group of children with spinal muscular atrophy of varying severity. The velocities were found to be reduced in infants with the severe infantile form of the disease( Werdnig-Hoffman type) but were normal in the less severe forms including the benign Kugelberg-Welander type.
The reduction of velocities in the severe form of spinal muscular atrophy is not as great as in demyelinating neuropathies and is probably due to predominant loss of the larger ( and therefore faster conducting ) nerve fibres.
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Moosa, A. MOTOR NERVE CONDUCTION VELOCITY IN SPINAL MUSCULAR ATROPHY-AN INDEX OF SEVERITY. Pediatr Res 8, 142 (1974). https://doi.org/10.1203/00006450-197402000-00099
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DOI: https://doi.org/10.1203/00006450-197402000-00099
