Abstract
The phosphoglyceride fatty acids of the aorta were studied in a group of 18 newborn infants with different gestational ages. All the infants had died during the earliest hours of life, before feeding. The total lipids, free cholesterol and lipid phosphorus were quantified in the lipid extract of the homogenized aorta, and no changes in their concentration were found throughout the period studied. As for the fatty acids, the following findings contrasting with those previously reported in brain tissue were observed as the gestational age went up: an increase of the w6 fatty acids, specially of the 20:4w6 with a slowing down of its elongation, and a decrease of the 18:0 in ethanolamine phosphoglycerides. In choline phosphoglycerides the 18:2w6 increased as the gestational age progressed, whereas the 18:0 and 18:lw9 did not vary. The 22:4w6/22:5w6 index increased in both phosphoglycerides but more significantly in lecithin. The w3/w6 ratio only increased clearly in choline phosphoglycerides.
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Ballabriga, A., Martinez, M. ABNORMALITIES OF TISSUE LIPIDS: AORTA FATTY ACIDS IN THE NEWBORN PERIO. Pediatr Res 8, 131 (1974). https://doi.org/10.1203/00006450-197402000-00028
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DOI: https://doi.org/10.1203/00006450-197402000-00028
