Abstract
A study has been carried out in 1246 high risk newborn infants to determine the frequency, evolution, variations and severity of retinal vascular changes secondary to oxygen therapy administered in the neonatal period. They ranged from 480 to 5,640 gm in birthweight and 26 to 44 weeks in gestational age. Retinopathy of prematurity (retrolental fibroplasia) was diagnosed in 40, of whom 2 are blind from end-stage cicatricial disease. Changes in the others varied from minor neovascularization of the temporal peripheral retina to more extensive vessel proliferation and from peripheral retinal scarring to traction and distortion of the retina at the posterior pole of the eye. Correlations between severity of the disorder and birthweight and gestational age will be presented as a basis for a new and more useful classification of the disease.
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McCormick, A., Pirie, G. & Segal, S. RETINAL OXYGEN TOXICITY. Pediatr Res 8, 448 (1974). https://doi.org/10.1203/00006450-197404000-00648
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DOI: https://doi.org/10.1203/00006450-197404000-00648
