Abstract
NAE excretion was studied in 30 children with oedemas/age of 2–10 yrs/. Plasma creatinine, urea nitrogen, Na were normal, GFR was slightly decreased. Blood acid-base equilibrium was shifted towards metabolic acidosis. Mean H+NAE excretion was significantly decreased before and arter NH4 Cl loading. Before loading it was 35, 75 uEq/min/1,73 m2, after loading in 3 and 5 hours 67,14 uEq/min/1,73 m2, 78,17 uEq/min/1,73 m2/respectively. Decrease in H+NH4 excretion was more significantly expressed then H+TA excretion. Drop in H+NAE excretion was positively correlated with diuresis, GFR, and tubular reabsorption of Na. Negative correlation between plasma t CO2 and H+NAE excretion was not obserwed in contrast to the healthy children. Children with nephrotic syndrom showed lower ability for H+NAE excretion before and after NH4Cl loading.
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Szmigiel, C. HYDROGEN ION EXCRETION IN NEPHROTIC SYNDROME IN CHILDREN. Pediatr Res 9, 863 (1975). https://doi.org/10.1203/00006450-197511000-00065
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DOI: https://doi.org/10.1203/00006450-197511000-00065
