Abstract
Left ventricular (LV) performance was determined by echocardiography in 44 black children with sickle cell anemia (SS), and a control group of 28 age-matched healthy black children (N). The SS children were divided into two subgroups according to the absence (I) or presence (II) of dyspnea and/or fatigue on mild effort. The results are:
Thus LV function was normal in asymptomatic SS children but was depressed in a significant proportion of symptomatic children with sickle cell anemia. Echocardlography can be used to identify the presence of LV dysfunction and establish the need for treatment of heart failure which coexists with and is partially responsible for the congested circulatory state frequently observed in sickle cell anemia.
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Rees, A., Stefadouros, M., Strong, W. et al. ECHOCARDIOGRAPHIC ASSESSMENT OF LEFT VENTRICULAR FUNCTION IN CHILDREN WITH SICKLE CELL ANEMIA. Pediatr Res 11, 398 (1977). https://doi.org/10.1203/00006450-197704000-00172
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DOI: https://doi.org/10.1203/00006450-197704000-00172
