Abstract
In studies on the lipoprotein system of cord serum, we have determined the lipid and apolipoprotein (apo-LP) levels in various perinatal conditions. Infants of normal gestation and weight (>2500g) were characterized by the following lipid levels (mg/dl): TG=43.5 ± 18.3; TC=71.3 ± 20.9; FC=16.8 ± 6.2; PL=125.2 ± 36.7 (n=257). There were no distinct differences in the lipid levels between prematurity, postmaturity, caesarean section and miscellaneous abnormalities. Apolipoprotein concentrations in random cord sera were as follows: A-I=86.7; A-II=57.5; ApoB= 26.9; C-I=5.9; C-II=3.1; C-III=6.6; ApoD=4.7; and ApoE=7.7 (mg/dl). All apo-LP concentrations were lower than those found in adult sera with ApoB levels representing the lowest one (25% of adult sera). The apo-LP levels of abnormal groups were similar to those of normals with the exception of reduced levels of A-I and A-II in prematures. Results of this study show that the lipid and apo-LP levels of cord sera are lower than those of adult sera and that perinatal problems have little effect on the cord serum lipoproteins. The availability of specific apoliprotein assays will provide additional data necessary for evaluating dietary and other factors affecting the development of the lipid transport system in humans.
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Mcconathy, W., Curry, M., Lane, D. et al. SERUM LIPIDS VS SERUM APOLIPOPROTEINS IN CORD BLOOD. Pediatr Res 11, 520 (1977). https://doi.org/10.1203/00006450-197704000-00899
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DOI: https://doi.org/10.1203/00006450-197704000-00899
