Abstract
Both hydrocephalia interna and ESS may be associated with endocrine disturbances and enlarged sella turcica which erroneousely suggest a pituitary tumour.Two pubertal girls were followed three years.Both presented ESS and CAS diagnosed by fractionated pneumotomoence-phalography. A progressive increase of the pituitary fossa followed a brisk intracranial hypertension. One patient had spaniomenorrhea and a low level of serum RIA gonadotropins with a high response to LRH showing secondary pituitary defficiency. The other girl had accelerated puberty and serum RIA gonadotropins in the range of normal adult woman but a low level of plasma cortisol and a reduced response to metyrapone. It shows that the intracranial hypertension and chronic hydrocephalia interna may produce ESS and opposite effects on gonadotropins secretion.
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Stoica, T., Coculescu, M., Login, X. et al. Congenital aqueductal stenosis (CAS) and empty sella syndrome(ESS) with two opposite patterns of gonadotropin secretion. Pediatr Res 12, 1095 (1978). https://doi.org/10.1203/00006450-197811000-00085
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DOI: https://doi.org/10.1203/00006450-197811000-00085
