Abstract
Serum cholesterol and triglyceride levels were determined in 17 children with various forms of anemia and varying rates of red cell production. Anemic patients had low serum cholesterol values, and a good correlation between hemoglobin and serum cholesterol levels was found. The serum triglycoride levels were below the mean of our reference material in 14 of the 17 patients, but thero was a wider scatter than of the cholesterol values. No relationship could be demonstrated between the rate of red cell production as Judged by reticulocyte counts, and serum cholesterol and triglycerides, respectively. These results and a few earlier studies indicate that all lipoprotein classes are reduced in individuals with uncomplicated anemias. This liypolipidemia can only partly be explained by the diluting effect of the increase in plasma volume accompanying anemia, and it is postulated that decreased lipoprotein synthesis may be a more important factor.
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Seip, M., Skrede, S. SERUM LIPIDS IN CHILDREN WITH ANEMIA. Pediatr Res 12, 71 (1978). https://doi.org/10.1203/00006450-197801000-00070
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DOI: https://doi.org/10.1203/00006450-197801000-00070
