Abstract
After the Mancini's et al (1965) method we investigated the levels of the main immunoglobulin classes - ,M,G - in healthy and sick children in age of 1 - 14 years with different group relationships to the isoantigenic systems of A.B.O and Rh.Various infectious rocesses occured in sick children: pseudotuberculosis n the form of the Far-Eastern scarlatiniform fever, nfectious and serum hepatitis, cholecystitis, salmonollosises, rheumatoid arthritis etc. Both in healthy and sick children rather distinct regularities in the genetic patterns of the immunoglobulin potential were detected in all the classes studied irrespective of the etiology and pathogenetic features of the infection. A particularly distinct dependence was revealed in the level of IgG, one of the functions of which is the close relation to the organism's predisposition to allergy. The obtained data allow to reveal the groups of the special risk and choose the exact individual approach to the patient's treatment.
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Motavkinaa, N., Gordevets, A., Miroshnichenko, V. et al. 29 THE GENETIC PATTERN OF THE IMMUNOGLOBUL IN POTENTIAL IN CHILDREN. Pediatr Res 13, 953 (1979). https://doi.org/10.1203/00006450-197908000-00045
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DOI: https://doi.org/10.1203/00006450-197908000-00045
