Abstract
It has been shown earlier that glomerular filtration rate /GFR/ and kidney size is increased in early childhood diabetes. The purpose of the present study was to investigate whether a connection sould be demonstrated between the kidney size and the metabolic control of the disease. Renal function and roentgenographic kidney size were measured in 8 children with newly diagnosed diabetes, in 22 insulin treated diabetic children with a short-term duration of the disease and in 12 matched controls aged 7-14 years. Kidney size and GFR were significantly increased in newly diagnosed diabetics and in 12 poorly controlled diabetic children, but there was no significant change of renal size or GFR in lo well-controlled diabetic children compared to the controls.The results suggest that there is a basic connection between the kidney size respectively the renal function and the metabolic control in early childhood diabetes.
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Madacsy, L. Kidney size and renal function in poorly and well-controlled diabetic children. Pediatr Res 13, 85 (1979). https://doi.org/10.1203/00006450-197901000-00098
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DOI: https://doi.org/10.1203/00006450-197901000-00098
