Abstract
Thyroid function as reflected in cord blood T4, T3, rT3 and TSH concentrations was assessed in a group of non-asphyxiated premature infants between 31 and 34 weeks gestation with RDS and compared to a rigidly controlled non-RDS population. Infants were matched for gestational age (GA), sex and birthweight. Results (as geometric mean with 95% confidence limits in parentheses) were as follows:
Hoteling's T2 test used for a global comparison of thyroid function as reflected in T4, T3 and rT3 concentrations failed to demonstrate a significant difference between the two groups (0.10>p>0.05). TSH concentrations also were similar in control and RDS infants (p>0.10). Conclusion: Maturation of hypothalamic-pituitary-thyroid function is not significantly delayed in infants who subsequently develop RDS.
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Klein, A., Foley, B., Foley, T. et al. 1342 CORD BLOOD THYROID FUNCTION STUDIES IN PREMATURE INFANTS WITH AND WITHOUT RESPIRATORY DISTRESS SYNDROME (RDS). Pediatr Res 15 (Suppl 4), 667 (1981). https://doi.org/10.1203/00006450-198104001-01371
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DOI: https://doi.org/10.1203/00006450-198104001-01371
