Abstract
The purpose of this study was to determine, 1) whether intralipid (IL) infusion in preterm infants leads to decrease in transcutaneous oxygen tension (TcPO2) and apnea, 2) whether change in TcPO2 is due to decreased pulmonary diffusion or increased oxygen utilization. TcPO2, oxygen consumption (VO2), carbon dioxide production (VCO2), respiratory quotient (RQ), respiratory rate, serum triglyceride (TG) & free fatty acid (FFA) were serially measured in 5 preterm AGA infants (B.W. 980-2430 gm) before and during a 4 hr IL infusion with peripheral parenteral alimentation. Total caloric intake ranged from 80-110 Kcal/kg.d. Infants remained in room air at constant environmental temperatures throughout the study.
No significant change in skin temperature occurred. Only one infant developed apnea during IL infusion with a simultaneous decrease in TcPO2. One additional infant had a decrease in TcPO2 during IL. A decrease in RQ occurred consistently in all 5 infants and 4/5 infants had an increase in VO2. Concl. 1) Apnea & change in TcPO2 were not consistently observed during IL infusion, 2) RQ values greater than 1.0 suggest the anabolic state of the infants, 3) Preterm infants are capable of adapting to changes in the available nutrients for oxidative metabolism.
Log in or create a free account to read this content
Gain free access to this article, as well as selected content from this journal and more on nature.com
or
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kwong, M., King, K., Kalhan, S. et al. 261 EFFECT OF INTRALIPID ON RESPIRATORY CALORIMETRY IN PRETERM INFANTS. Pediatr Res 15 (Suppl 4), 483 (1981). https://doi.org/10.1203/00006450-198104001-00272
Issue date:
DOI: https://doi.org/10.1203/00006450-198104001-00272
