Abstract
We have evaluated the influence of postnatal age, energy intake(EI) and weight gain(Wt.G) on metabolic rate(MR), in 28 studies on 13 appropriate for gestational age formula fed(SMA 20/24) VLBW infants(mean±SE BWt:1155±39g; gest.age: 29.3±0.4 wks). Study age ranged from 5-43d, Wt. G from 0-28g/kg.d, energy intake from 52-169 Kcal/kg.d. MR measured by continuous open circuit indirect calorimetry ranged from 47-70 Kcal/kg.d. MR increased with age in the first 2 weeks(Fig.I; r=0.85). A similar relationship was found for energy intake and weight gain with increasing age. Multiple linear regression analysis shows that MR correlates with energy intake(Fig.II; r=0.88) and rate of weight gain (Fig.III; r=0.86). The interdependence of these 3 parameters(MR=38+0.13EI+0.36Wt.G; r=0.93) should be considered in the evaluation of energy metabolism under different clinical conditions or therapeutic and nutritional regimes. Changes in MR with postnatal age are modulated by increasing EI and Wt.G.
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Chessex, P., Reichman, B., Verellen, G. et al. 531 INFLUENCE OF AGE, ENERGY INTAKE, AND WEIGHT GAIN ON METABOLIC KATE IN THE VERY LOW BIRTHWEIGHT(VLBW) INFANT. Pediatr Res 15 (Suppl 4), 529 (1981). https://doi.org/10.1203/00006450-198104001-00544
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DOI: https://doi.org/10.1203/00006450-198104001-00544
