Abstract
Premature infants between 1000 and 1600g were assigned at 3 days of age to one of 4 groups, and fed a standard formula in which only the proportion of PUFA was varied by changes in the fat blend, and in which the vitamin E:PUFA ratio was kept constant. Sequential blood sampling showed a progressive rise in serum HDL levels in virtually all infants by 20 days of age (p<.01). Total cholesterol levels rose significantly (p<.05) by 20 days only in the group on the lowest concentration (16%) of PUFA.
The results demonstrate the ability of very-low-birth-weight infants to exhibit rapid metabolic adjustments in response to variations in dietary PUFA levels, though the long-term significance is conjectural at this time.
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Fineza, B., Rudolph, N., Parekh, A. et al. 548 RESPONSE OF SERUM TOTAL CHOLESTEROL AND HIGH DENSITY LIPOPROTEIN (HDL) LEVELS IK PREMATURE INFANTS TO VARIATIONS IN DIETARY LEVELS OF POLYUNSATURATED FATTY ACIDS (PUFA). Pediatr Res 15 (Suppl 4), 532 (1981). https://doi.org/10.1203/00006450-198104001-00561
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DOI: https://doi.org/10.1203/00006450-198104001-00561
