Abstract
Increased neonatal prematurity, morbidity, and mortality is reported to be associated with chorioamnionitis(chorio). The present study was designed to determine the effects of chorio on the incidence of neonatal bacterial infections, hyaline membrane disease(HMD), asphyxia, and mortality. The charts of mothers with chorio and their infants were reviewed retrospectively from Jan 1980-Dec 1982. Maternal chorio was defined as fever >100.4, tender lower abdomen, and/or leukocytosis >20,000. The control for each study patient was defined as the next live born infant with a birthweight(BW)within 100gm. In the study population 71% of the infants had a BW of <2500gm. Bacterial infection, HMD, and mortality were not significantly different in the study and control groups. However, the incidence of asphyxia was significantly higher in the study group(p value <025).
From this data it appears that maternal chorio is significantly associated with asphyxia in the neonate but not directly with neonatal infection.
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Rhodes, P., Ferguson, M. & Puckett, C. THE FFECTS OF CHORIOAMNIONITIS ON THE NEONATE. Pediatr Res 18 (Suppl 4), 342 (1984). https://doi.org/10.1203/00006450-198404001-01495
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DOI: https://doi.org/10.1203/00006450-198404001-01495
