Abstract
SEP's were studied in four chronically instrumented fetal sheep (FS) (GA 110-131 days) during normoxia and partial occlusion of maternal internal iliac arteries (IIA). Two animals had ovarian arteries (OA) ligated. SEP electrodes: recording-subdural at C-4 (international 10-20 system); reference-nasal bone; ground-right forelimb. Stimulating electrodes: left radial nerve. SEP configuration was consistent, latencies and amplitudes were variable. In two animals without OA ligation, fetal hypoxia could not be induced by occluding the maternal IIA's. In two animals with OA ligation, prolonged partial occlusion of IIA's resulted in the following ABG's:
In FS I no change in SEP occurred. In fetus II SEP was extinguished. SEP A is during normoxia (FS II). Latencies (mean ± SD, n=17) are N1=7.1 ± 0.68, N2=15.5 ± 1.32, P1=30.5 ± 3.00, N3=65.8 ± 12.03, P2=129.8 ± 18.20. SEP B was seen in the hypoxic period. 1) SEP can be reproducibly recorded in FS. 2) GA, degree of hypoxia, type and time course of acidosis may affect SEP during hypoxia.
Log in or create a free account to read this content
Gain free access to this article, as well as selected content from this journal and more on nature.com
or
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Matson, J., Person, R., Carson, J. et al. SOMATOSENSORY EVOKED CORTICAL POTENTIALS (SEP) IN A MODEL OF FETAL HYPOXIA. Pediatr Res 18 (Suppl 4), 379 (1984). https://doi.org/10.1203/00006450-198404001-01719
Issue date:
DOI: https://doi.org/10.1203/00006450-198404001-01719
