Abstract
Summary: Studies performed on iron-deficient and control rats demonstrated that oxidative energy production (phosphorylation) by mitochondria from iron-deficient red and intermediate skeletal muscles was greatly reduced with pyruvate-malate, succinate, and a-glycerophosphate as substrates. Although phosphorylation was also decreased in iron-deficient white skeletal muscle with succinate and pyruvate-malate as substrates, no change was found with a-glycerophosphate as substrate.
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Mackiler, B., Grace, R. & Finch, C. Iron Deficiency in the Rat: Effects of Oxidative Metabolism in Distinct Types of Skeletal Muscle. Pediatr Res 18, 499–500 (1984). https://doi.org/10.1203/00006450-198406000-00001
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DOI: https://doi.org/10.1203/00006450-198406000-00001
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