Abstract
Histologic and direct immunologic effects of testicular torsion on the contralateral testicle were investigated in prepubertal Chinese hamsters. Four study groups were established. I) Left orchiectomy only, II) sham surgery (scrota1 incision) III) 720° left testicular torsion with left orchiectomy 24 hours later, IV) 720° torsion of left testicle with detorsion after 24 hours. Biopsies of the contralateral testicle were performed at one week, one month, and six months after the indicated procedure. Testicular tissue was examined for immunofluorescent activity using fluorescent labeled goat anti-hamster IgG and compared to positive controls. Fluorescence was graded neg, tr, 1 – 4+, depending on the degree of fluorescence of the basement membrane, interstitium, and individual germinal cells. Control orchiectomy specimens, Groups I and I1 showed some variability in immunofluorescence between negative and 1+. Group III specimens showed 7/41 (17%) negative, 23/41 (56% tr, 11/41 (27%) 1+ and 1/41 (2%) 3+. Group IV specimens revealed 2/18 (11%) negative, 12/18 (67%) tr, and 4/18 (22%) 1+. Immunologic appearance did not appear related to time after torsion, or differ between control and experimental animals. Representative histologic specimens demonstrated no tubular damage.
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Henderson, J., Smey, P., Cohen, M. et al. 981 THE EFFECT OF UNILATERAL TESTICULAR TORSION ON THE CONTRALATERAL TESTICLE IN PREPUBERTAL CHINESE HAMSTERS. Pediatr Res 19, 274 (1985). https://doi.org/10.1203/00006450-198504000-01011
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DOI: https://doi.org/10.1203/00006450-198504000-01011
