Abstract
A system was designed to dispense precise volumes of prefiltered, sterile, quality blood for immediate infusion into designated infants without waste. In the blood bank, the volume ordered was aspirated from the primary blood bag through a micro-aggregate filter into a plastic syringe. The syringe was capped, taken to the nursery in a lock-top plastic bag and was directly attached to an infusion pump. In practice, a transfusion may require hours to complete; thus, both quality and sterility of blood stored in syringes were studied. Blood was drawn from 10 bags (packed RBC, 5 days old) through filters into two syringes. Each bag and one syringe were stored at 4°C, the other syringe at 22°C. Samples (N=70) were taken after 0, 3, 6 and 24 hr. Quality and sterility of RBC in syringes was equal at all times to that of blood bags stored at 4°C in the blood bank except for a decreased (p < .05) pH after 24 hr at 22°C. Only baseline (0 hr) and extreme (24 hr) mean values are shown here:
Blood, plasma, platelets and granulocytes can be dispensed similarly. Thus, unit dose dispensing provides precise quantities of quality, ready-to-infuse blood products for individual neonates.
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Strauss, R., Elbert, C., Crawford, G. et al. 1537 UNIT DOSE, READY-TO-USE BLOOD PRODUCTS FOR NEONATES. Pediatr Res 19, 367 (1985). https://doi.org/10.1203/00006450-198504000-01561
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DOI: https://doi.org/10.1203/00006450-198504000-01561
