Abstract
Two hundred and thirty-six neonates with convulsions (90.8% of survivors) from a regional perinatal program had detailed neuro-developmental follow-up as part of a cohort of 934 neonatal graduates assessed at 3.5 years of age. All children with known syndromes or malformations of the central nervous system were not included. Fifty-five percent were term neonates.
The types of clinical neonatal convulsions included: generalized tonic with or without generalized clonic (n=129)(36.4% handicapped), multifocal clonic (n=82)(35.4% handicapped), subtle or primitive (n=81)(33.3% handicapped), symmetrical myoclonic (n= 6)(66.7% handicapped), and unspecified (n=12)(50.0% handicapped).
‘Handicapped’ was also related to the number of types of anti-convulsants required to control the convulsions (chi square = 104.7, p= <0.0001), but was not related to the age of onset of convulsions.
Whereas previous studies have related seizure type and outcome, this study suggests a strong relationship between the number of different types of clinical neonatal convulsions per child and outcome.
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Robertson, C. 1702 NEONATAL CONVULSIONS: TYPE AND OUTCOME. Pediatr Res 19, 394 (1985). https://doi.org/10.1203/00006450-198504000-01720
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DOI: https://doi.org/10.1203/00006450-198504000-01720
