Abstract
Two-month-old rats were fed for 7 days a low carbohydrate (LC) [BBA 676:108] diet; subsequently they were force fed three times in 12 hours (to insure a controlled intake of food) carbohydrate diets (40 cal%) containing either glucose (Glu), galactose (Gal), fructose (Fru) or α-methylglucoside (α-MG). Activity of sucrase (SA), lactase (LA), and amount of immunoreactive lactase (IRL) and immunoreactive sucrase (IRS) [using electroimmunoassay] were determined in jejunal mucosa.
*Mean±SEM; a-c stat signif from each other if not sharing a common superscript. N (group): 4-7.
Conclusion. (a) All the monosaccharides studied evoked a parallel increase of activity of disaccharidases and corresponding immunoreactive proteins as demonstrated by the constant ratio of enzyme activity/immunoreactive protein. (b) Fructose was the most effective “inducer”; the effect of α-methylglucoside, a non-metabolizable sugar, is very intriguing.
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Goda, T., Bustamante, S. & Koldovskft, O. 654 EFFECT OF FEEDING VARIOUS MONOSACCHARIDES ON THE ACTIVITY AND THE IMMUNOREACTIVE AMOUNT OF LACTASE AND SUCRASE IN ADULT RAT JEJUNUM. Pediatr Res 19, 219 (1985). https://doi.org/10.1203/00006450-198504000-00684
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DOI: https://doi.org/10.1203/00006450-198504000-00684
