697 MACRO- AND MICRONUTRIENT INTAKES IN CHILDREN WITH CROHN'S DISEASE(CD)

Abstract

Poor nutrition has been associated with growth failure in the adolescent with long-standing CD. We have used 24-hour dietary recall to assess macro- and micronutrient intakes in 11 Tanner I-II CD patients (ages 8-14.5 yrs) within 6 months of diagnosis. 5 had linear growth failure(<4cm/yr). 8 had a mean weight deficit for height (±SE) of 9.2±2.5 kg. All had minimal disease activity (CDAI). 6 received sulfasalazine and 3 prednisone. Daily nutrient requirements were defined by 2 different methods based on each patient's ideal body weight (IBW) for actual height: Recommended Dietary Allowance (RDA) for chronological age, and caloric requirement for healthy Tanner I-II children (86 kcal/kg IBW). While 7/11 had 90% of expected caloric intake for chronological age, only 2/11 had adequate caloric intake for pubertal status. Mean caloric intake (±SE) was 68±7% of that recommended for healthy Tanner I-II children. Mean protein intake was 2.1±0.2 gm/kg IBW. Carbohydrate constituted 44±2% of calories, and fat 41±2%. Micronutrient intakes <70% RDA included: Vit D and folacin(11/11) zinc, calcium.magnesium, Vit B6 (6/11); iron (4/11); niacin, Vits C and E (3/11); thiamin (2/11); riboflavin (1/11). Phosphorus and Vit B12 intakes were adequate. Vit A intake >150% RDA was found in 8/11. Similar dietary abnormalities including caloric intake were found in patients with and without growth failure. Disturbances in both caloric and micronutrient intakes are common in Tanner I-II children with CD and require appropriate nutritional intervention.

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