Abstract
Most neonates on total parenteral nutrition (TPN) receive insufficient calcium for normal bone growth and hypercalciuria has been reported. To determine whether supplemental calcium would be retained, we compared the effects of two calcium intakes on short term calcium balance in 6 neonates of gestational age 42±3 weeks (x±SD): a standard TPN solution was given for 1 week followed by a high calcium TPN solution for 1 week; 24 hour urine collections were made at the end of each week; no diuretics were given. Serum calcium levels were normal during the study. Calcium balance data are shown below:
Phosphorus concentration was the same in both of the TPN solutions and no difference in phosphorus excretion was observed. We conclude that with a 2.5 fold increase in calcium intake, there was a 3.4 fold increase in calcium retention. Increased calcium supplementation improves calcium balance in neonates receiving TPN.
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Subramanian, N., Merritt, R., Cheng, M. et al. 736 INCREASED CALCIUM SUPPLEMENTATION IN NEONATES RECEIVING TOTAL PARENTERAL NUTRITION RESULTS IN IMPROVED CALCIUM RETENTION. Pediatr Res 19, 233 (1985). https://doi.org/10.1203/00006450-198504000-00766
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DOI: https://doi.org/10.1203/00006450-198504000-00766
