Abstract
Patients with IgE-mediated hypersensitivity to pollens are frequently also hypersensitive to allergens in other plant tissues. For example, patients with immediate hypersensitivity to birch pollen are frequently sensitive to a variety of raw fruits, vegetables and/or nuts.
Crossreaotivity of IgE antibodies was investigated serologically by RAST-inhibition assays and Western biota with human IgE antibodies and crossreacting monoclonal antibodies. Apart from periodate-susceptible crossreacting carbohydrate determinants, several periodate-resistent crossreacting determinants were detected on protein components of 20, 18 and 14 kD, respectively. The 20 kD component present in birch pollen seems to be responsible for the crossreactivity with fruits, whereas the 18 kD component of birch pollen seems to be responsible for the crossreactivity with grass pollen, potato and fruits. The cross-reacting determinant on the 11 kD component is present in pollens (e.g. grass pollen) and other vegetable materials (e.g. potato).
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Calkhoven, P., Aalberse, M., Pos, O. et al. 34 CROSSREACTIVITY OF IgE ANTIBODIES BETWEEN VEGETABLE FOODS AND POLLEN. Pediatr Res 20, 1039 (1986). https://doi.org/10.1203/00006450-198610000-00088
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DOI: https://doi.org/10.1203/00006450-198610000-00088
