Abstract
We have previously reported close associations between the results of ultrasound brain-scans in infants born at less than 33w gestation and their neurodevelopmental status at 18 months of age (Stewart AL et al, Arch Dis Child 1983; 58: 598-604). To find out whether this status had changed at 4 years, neurological examinations and tests of cognitive function were carried out (see table).
In general, neurodevelopmental status at 18 months was substantiated at 4 years. Disorders recognised at 4 years in previously unaffected infants included deficits of vision and of cognitive function, behavioural disorders and epilepsy. 4 infants no longer had minor disorders but as a group infants assigned this status at 18 months (usually because of abnormalities of tone and reflexes) scored worse on tests of cognitive function than infants considered to be normal at 18 months.
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Hamilton, P., Costello, L., Stewart, A. et al. 40 ULTRASOUND BRAIN-SCANS IN VERY PRETERM INFANTS AND OUTCOME AT 18 MONTHS AND 4 YEARS OF AGE. Pediatr Res 20, 1040 (1986). https://doi.org/10.1203/00006450-198610000-00094
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DOI: https://doi.org/10.1203/00006450-198610000-00094