Abstract
We have evaluated 30 children with HIV infection ranging in age from 4-1/2 months to 8-1/2 years, and 30 controls matched for age, sex, and race/ethnicity for growth, head size, craniofacial dysmorphism, dermatoglyphics and other physical features. All patients and their mothers were serologically positive for HIV-antibody.
Aside from growth failure and microcephaly (which are attributable to chronic infections and central nervous system lesions in AIDS patients) there were no significant differences in clinical findings (including dermatoglyphics) between patients and controls. A previous report describing craniofacial dysmorphism in children with AIDS noticeably lacked in comparison with normal controls. We conclude that although there is evidence for intrauterine transmission of HIV infection causing immunological impairment, there is no evidence for “embroypathy”.
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Sheikh, T., Qazi, Q., Fikrig, S. et al. LACK OF EVIDENCE FOR CRANIO-FACIAL DYSMORPHISM IN CHILDREN WITH AIDS. Pediatr Res 21 (Suppl 4), 230 (1987). https://doi.org/10.1203/00006450-198704010-00384
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DOI: https://doi.org/10.1203/00006450-198704010-00384
