Abstract
Angiographic and animal studies have shown that most of the diastolic flow in the PDA originates from the descending aorta, potentially leading to abdominal ischemia. We studied blood flow velocities directly in renal (RA) and internal carotid arteries (CAI) of 10 infants (body weight 620-1485g, gestat. age 26-33 wks) with PDA and after surgical ligation by Doppler ultrasonography. Peak systolic (Vs), enddiastolic (Vd), time averaged maximal velocities (TAM), resistance indices (RI) were determined.
With PDA, Vd was markedly decreased in the RAs and even reversed in 7/10 infants. In the CAI, however, Vd was retrograde only in 3/10 infants and TAM did not show any difference with surgical ligation.
Our findings indicate that a PDA may also result in a steal of blood away from the kidneys. This is more pronounced than in the CAL.
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Bõrnelburg, T., Jorch, G. RENAL VERSUS CEREBRAL BLOOD FLOW VELOCITIES IN PRETERM INFANTS WITH PATENT DUCTUS ARTERIOSUS. Pediatr Res 26, 505 (1989). https://doi.org/10.1203/00006450-198911000-00037
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DOI: https://doi.org/10.1203/00006450-198911000-00037
