Abstract
In order to evaluate the improvement of erythropoiesis following renal transplantation ( RT ) hematological parameters and serum erythropoietin ( EPO ) were measured before and sequentially at the months 1, 2, 3, 6, 9, 12 after grafting 34 consecutives renal transplant recipients { mean age: 12.3 ± 6.4 (SD)}. EPO was estimated by using an ELISA {intra- and interassay coefficients of variations were 4.S % and 6.8 %, respectively.
Results: Pretransplant mean EPO was 18 ± 8.2 (SD) mU/ml, hematocrit was low { (27.8 ± 8(SD) %}. After RT hematological parameters and EPO values in patients with immediate graft function were as follows:
Conclusion; Pretransplant Ht/EPO- ratio were low. One month after renal transplantation EPO levels increases significantly and decreases subsequently to normal values.
Ht/EPO-ratio increased twelve months after RT due to normalisation of feedback regulation between erythropoietin and hematocrit.
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Khoss, A., Steger, H., Böck, A. et al. 90 SERUM ERYTHROPOIETIN LEVELS AND HEMATOCRIT AFTER RENAL TRANSPLANTATION IN CHILDREN. Pediatr Res 28, 292 (1990). https://doi.org/10.1203/00006450-199009000-00114
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DOI: https://doi.org/10.1203/00006450-199009000-00114
