Abstract
ABSTRACT: Fibrinogen levels were measured in 5- to 17-y-old children (n = 3047; 40% black and 49% female), from a well-defined biracial community. No significant race and sex differences in fibrinogen levels were observed, but levels increased (p < 0.001) with age or sexual maturation in black females. Adjusted for age, fibrinogen concentrations were positively correlated with ponderal index (weight/height3) (0.09-0.22,p < 0.01), triceps skinfold thickness (0.10-0.23,p < 0.05), and subscapular skinfold thickness (0.13-0.24,p < 0.01) in all race-sex groups. Weak correlations were found between fibrinogen level and blood pressure and lipoprotein components for some of the race-sex groups, but these become nonsignificant or minimal after adjustment for ponderal index and skinfolds. A positive correlation (0.12-0.16,p < 0.01) was found between fibrinogen and white blood cell count for Caucasians, which still held after adjustment for ponderal index and skinfolds. In a stepwise regression, ponderal index, white blood cell count, and HDL cholesterol showed an independent association with fibrinogen.
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Bao, W., Srinivasan, S. & Berenson, G. Plasma Fibrinogen and Its Correlates in Children from a Biracial Community: The Bogalusa Heart Study. Pediatr Res 33, 323–326 (1993). https://doi.org/10.1203/00006450-199304000-00003
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DOI: https://doi.org/10.1203/00006450-199304000-00003
