Abstract
Nonoliguric Hyperkalemia (HK) is frequently observed in VLBWI. We prospectively studied 85 VLBWI (BW<1500 g) in order to determine the frequency of HK (serum potasium>6.4 mmol/L) and its relationship with BW, diuresis and urea production. Potasium level was measured in the 1st, 3rd and 7th day of life. The BW (x±SD) was 1161 g ± 249 and gestational age was 29 weeks ± 1.9. a significantly high incidence of HK in neonates < 1000gr. was observed (7/32 vs.1/52, p <.01). No relation was found between diuresis and HK. Both groups with and without HK showed oliguria in the first day.
The urea production was similar in both groups though very high (12 mmol/Kg/d). This catabolic effect could explain the high rate of potasium production without renal failure which associated to the first day oliguria could be the necesary condition for the development of HK in this group of patients.
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Fustiñana, C., Anglada, A. DIURESIS AND SERUM POTASIUM LEVELS IN VLBWI.. Pediatr Res 33, 661 (1993). https://doi.org/10.1203/00006450-199306000-00041
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DOI: https://doi.org/10.1203/00006450-199306000-00041