Iron Metabolism in Children with Juvenile Rheumatoid Arthritis (JRA).2

Background: The etiology of chronic anemia in children with JRA is poorly understood. We utilized stable and radioactive Fe isotopes to determine Fe absorption, RBC incorporation and intraarticular deposition in children with JRA.

Subjects: 5 children (age range 3-17 yr) with polyarticular JRA(20 ± 12 months since diagnosis), of whom 3 were anemic (Hgb < 11 g/d1) and 5 healthy, age- and sex-matched children.

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