Background: The polypeptide angiogenin, a normal constituent of human plasma, might be involved in endothelium homeostasis, angiogenesis and neovascularization accompaning various diseases. This study aimed at determining angiogenin serum concentrations (ASC) in the perinatal period of healthy newborns and at having a baseline for this protein, which in the future may serve as a diagnostic index in developmental errors of the placenta and/or newborn.

Subjects- Interventions: One ml of blood was drawn on day 1 (N1) and 4 (N4) of life from 30 healthy fullterm neonates and ASC were measured by an enzyme immunoassay using a commercially available kit. In 10 cases ASC were measured also in the maternal serum (MS) before delivery and the umbilical cord serum (UC).

Log in or create a free account to read this content

Gain free access to this article, as well as selected content from this journal and more on nature.com

Access through your institution

or

Sign in or create an account
Continue with Google
Continue with ORCiD