Hyper-Releasibility of Mast Cells Among Family Members of Babies Expired of Sudden Infant Death Syndrome and Among Babies Post Apparent Life Threatening Events and Their Famillies.

Abstract □ 110

Background. Allergic and anaphylactoid reactions caused by increased degranulation of mast cells have been proposed as possible pathophysiological mechanisms in SIDS. This mast cells hyper-releasibility, if exists, would be an endogenous defect of the mast cells and, therefore, genetically inherited. Hence, this defect could be found also in family members of SIDS cases.

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