Glucocorticoid Induced Rise in Serum Leptin Is Associated with Poor Growth in Sick Preterm Infants

Abstract 1710 Neonatology: Clinical Studies in the Premature Infant Platform, Tuesday, 5/4

Background: Sick preterm infants treated with dexamethasone(dx) may have growth failure in spite of adequate nutrition. We have previously reported that dx leads to a rise in serum leptin (Peds Res 1998;43:338-43). Purpose: To study the effect of dx induced increase in serum leptin on weight gain pattern of sick preterm infants in relation to total caloric intake.

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