Neonatal Seizures Exacerbate Mild to Moderate Hypoxic-Ischemic (HI) Brain Damage

Abstract 2057 Perinatal Brain Injury: Patterns and Mechanisms Platform, Tuesday, 5/4

Introduction: Perinatal hypoxia-ischemia (HI) is the most common precipitant of seizures in the first 48-72 hrs of a newborns' life. Despite being treated as a medical emergency in neonatal intensive care units, whether or not neonatal seizures contribute to hypoxic-ischemic brain damage remains unknown. The current study was therefore undertaken to clarify whether or not seizures in the newborn contribute to the brain damaging effects of an asphyxial insult.

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