Abstract • 104

The effect of iron deficiency anemia (IDA) on CD71 expression by peripheral blood lymphocytes and monocytes was studied in 43 children. Eighteen healthy age-matched children served as controls. CD71 bearing lymphocytes and monocytes were enumerated by flow cytometric analysis. At diagnosis, the mean +/- SD of CD71+ lymphocytes and monocytes was 5.9 +/- 0.76% and 23.0 +/- 4.0% in IDA patients and 12.6 +/- 0.98 % and 27.6 +/- 6.6 % in controls, respectively. Differences between CD71+ lymphocytes and monocytes were significant: p <0.001, and p = 0.038 respectively. In IDA patients a statistically significant correlation was seen between CD71+ lymphocytes and monocytes vs Hb, Hct, and MCV (p <0.001 in all instances). After 30 days of oral iron therapy the number of CD71+ lymphocytes and monocytes increased significantly.

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