Abstract 254 Poster Session III, Monday, 5/3 (poster 114)

Introduction: The choice of mechanical ventilation strategy influences the course of lung disease. Strategies that permit alveolar closure and cyclic overdistension can exacerbate preexisting lung injury. We hypothesized that lung recruitment strategies that avoid cyclic overdistension of alveoli while maintaining adequate functional residual capacity would be associated with more favorable physiologic outcomes in a model of acute lung injury.

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