Abstract
Objective: Immun response against pertussis can be induced by infection and/or vaccination and vaccine induced immunity is known to wane within the following decade. Our aim was to assess the pertussis immun response among adolescent girls in Edirne province in Turkey and to determine its relationship with some parameters.
Material and Method: The serum sample collection, representing 12 to 17 years old adolescent girls was consisted of 359 subjects and was selected from school lists by systematic and random sampling which weighted by age, urban-rural residence strata proportional to the corresponding distributions in Edirne population. Pertussis immunity was determined by in-house ELISA method and anti-PT and anti-FHA antibody titers were measured quantitatively.
Results: The overall ratio of having protective levels of antibody (>10 EU/ml) were 95,3% and 97,2% for anti- pertussis toxin and anti- filamentous hemagglutinin, respectively. The ratio of antibody in protective levels for anti- pertussis toxin and anti- filamentous hemagglutinin in 12 and 14 years age group were found as 94,1%; 97,0%; in 15 and 17 years age group 97,5% and 97,5%; in rural area 96,7%; 97,5%, in urban area 94,5%, 97,5%, respectively (p>0.05).
Conclusion: The high ratio of having protective levels of antibodies might be an indicator of the previous infections that is a threat for infants who have not completed primary immunization. In this respect, adult immunization should be discussed.
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Vatansever, U., Éöplü, N., Öner, N. et al. 394 Seroprevalance of Bordetella Pertussis Antibodies Among Healthy Adolescent Girls in Edirne. Pediatr Res 58, 422 (2005). https://doi.org/10.1203/00006450-200508000-00423
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DOI: https://doi.org/10.1203/00006450-200508000-00423
